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Qui bloquerait les effets nuisibles du temozolomide TMZ de la voie AKT-mTOR. Synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A. Akt favorise la survie en inhibant des proapoptotiques et en stimulant des anti-apoptotiques. Pathways controlling protein anabolism has been reported in muscle tissue. La voie de signalisation en aval (Akt/mTOR/p70S6k/4EBP1. This protein is considered as a tumor-suppressor. The oncogenic form of Akt, a serine-threonine kinase, is multifunctionnal. One of its function is to induce
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